Torque's Combitor Tablets contain Ibuprofen & Paracetamol, which act as anti-inflammatory & analgesics.
Pharmaceutical Dosage Form:
Tablets
Route of Administration:
Oral
Composition:
Each uncoated tablet contains:
- Ibuprofen I.P. 400 mg
- Paracetamol I.P. 325 mg
- Excipients q.s.
Mechanism of Action:
Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing hormones that cause inflammation and pain in the body. Paracetamol is an antipyretic (fever reducer) and analgesic (pain reducer).
Indications:
For temporary relief of pain associated with: headache, migraine, backache, period pain, dental pain, muscular pain, dysmenorrhea, cold and flu symptoms, sore throat and fever.
Dosage:
As directed by the Physician.
CONTRAINDICATIONS:
This product is contraindicated for use:
• in patients with known hypersensitivity reaction to paracetamol, ibuprofen, other NSAIDs or to any of the excipients.
• in patients who have experienced asthma, urticaria, or allergic-type reactions after taking acetylsalicylic acid or other NSAIDs.
• In patients with active or a history of gastrointestinal bleeding or peptic ulceration.
DRUG INTERACTIONS:
Fluconazole, Voriconazole increases plasma concentration of Ibuprofen.
Antiplatelet effect of Aspirin possibly reduced by Ibuprofen.
Excretion of Baclofen, Methotrexate reduced by Ibuprofen.
Increased risk of nephrotoxicity when ibuprofen given with Tacrolimus.
Lixisenatide possibly reduces the absorption of Paracetamol
Ketoconazole advises avoid concomitant use with Paracetamol.
Carbamazepine possibly accelerates metabolism of Paracetamol.
Colestyramine reduces absorption of Paracetamol.
Anticoagulant effect of coumarins possibly enhanced by prolonged regular use of Paracetamol.
Metoclopramide increases the rate of absorption of Paracetamol.
SIDE EFFECTS:
This medication may cause abdominal pain, diarrhea, dyspepsia, nausea, stomach discomfort, vomiting, dizziness, headache, nervousness, rash (including maculopapular type), and pruritus.
PRECAUTIONS:
Bronchospasm may be precipitated in patients suffering from or with a previous history of bronchial asthma.
Ibuprofen should not be given to patients in whom aspirin and other non-steroidal anti-inflammatory drugs induce the symptoms of asthma, rhinitis or urticaria.
An overdose of paracetamol may cause liver damage
STORAGE:
Store protected from moisture, at a temperature below 30°C.
